Powering membrane traffic in endocytosis and recycling pdf

ثبت نشده
چکیده

Powering membrane traffic in endocytosis and recycling. Thierry Soldati and Manfred Schliwa. Abstract Early in evolution, the diversification.Endocytic trafficking and subsequent recycling of plasma-membrane components is essential for cell viability. They direct the movement of vesicular carriers. The subjects of this review are the motors that power the transport steps along the endocytic and recycling pathways, their modes of attachment.Rab GTPases control intracellular vesicle traffic by acting as regulatable switches that recruit effector. Powering membrane traffic in endocytosis and recycling.Recent work focused on the role of membrane trafficking during cytokinesis and. That endocytic recycling is required for abscission 1, 2. 2006 Powering membrane traffic in endocytosis and.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Studies of synaptic vesicle endocytosis in the nematode C. elegans.

After synaptic vesicle exocytosis, synaptic vesicle proteins must be retrieved from the plasma membrane, sorted away from other membrane proteins, and reconstituted into a functional synaptic vesicle. The nematode Caenorhabditis elegans is an organism well suited for a genetic analysis of this process. In particular, three types of genetic studies have contributed to our understanding of synapt...

متن کامل

Abscisic Acid Triggers the Endocytosis of the Arabidopsis KAT1 K+ Channel and Its Recycling to the Plasma Membrane

Membrane vesicle traffic to and from the plasma membrane is essential for cellular homeostasis in all eukaryotes. In plants, constitutive traffic to and from the plasma membrane has been implicated in maintaining the population of integral plasma-membrane proteins and its adjustment to a variety of hormonal and environmental stimuli. However, direct evidence for evoked and selective traffic has...

متن کامل

Rme-1 regulates the recycling of the cystic fibrosis transmembrane conductance regulator.

Endocytic motifs in the carboxyl terminus of cystic fibrosis transmembrane conductance regulator (CFTR) direct internalization from the plasma membrane by clathrin-mediated endocytosis. However, the fate of such internalized CFTR has remained unknown. Internalized membrane proteins can be either targeted for degradation or recycled back to the plasma membrane. Using cell surface biotinylation a...

متن کامل

Actin dependence of polarized receptor recycling in MDCK cell endosomes

Mammalian epithelial cell plasma membrane domains are separated by junctional complexes supported by actin. The extent to which actin acts elsewhere to maintain cell polarity remains poorly understood. Using latrunculin B (Lat B) to depolymerize actin filaments, several basolateral plasma membrane proteins were found to lose their polarized distribution. This loss of polarity did not reflect la...

متن کامل

Molecular structure, function, and dynamics of clathrin-mediated membrane traffic.

Clathrin is a molecular scaffold for vesicular uptake of cargo at the plasma membrane, where its assembly into cage-like lattices underlies the clathrin-coated pits of classical endocytosis. This review describes the structures of clathrin, major cargo adaptors, and other proteins that participate in forming a clathrin-coated pit, loading its contents, pinching off the membrane as a lattice-enc...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015